DBCO試劑可用于標記疊氮化物修飾的生物分子

產品名稱：DBCO-PEG-SH DBCO-PEG-Thiol

中文名稱：二苯并環辛炔-聚乙二醇-巰基

PEG分子量：1k，2k，3.4k，5k，10k其他分子量可定制

存儲條件：≤-4℃低溫干燥保存

產品外觀: 固體或黏稠液體，取決于分子量

常用溶劑：溶于大部分有機溶劑，如：DCM、DMF、DMSO、THF等等。在水中有很好的溶解性

DBCO（二苯并環辛炔）聚乙二醇硫醇（DBCO-PEG-SH）衍生物無需任何金屬催化劑即可進行化學反應。菌株促進的環辛炔和疊氮化合物的1,3-偶*環加成反應，也稱為無銅點擊反應，是一種生物正交反應，可使兩個分子在水溶液中共軛。DBCO-PEG衍生物在水相緩沖液中具有快速動力學和穩定性。DBCO試劑可用于標記疊氮化物修飾的生物分子，而不需要有毒的銅催化劑。聚乙二醇化可以增加肽和蛋白質的溶解性和穩定性，并降低其免疫原性。它還可以抑制帶電分子與修飾表面的非特異性結合。

DBCO (dibenzocyclic octyne) polyethylene glycol mercaptan (DBCO-PEG-SH) derivatives can conduct chemical reactions without any metal catalyst. The 1,3-dipolar cycloaddition reaction of cyclooctyne and azide compounds promoted by the strain, also known as copper free click reaction, is a bioorthogonal reaction, which can make two molecules conjugate in aqueous solution. DBCO-PEG derivatives have fast kinetics and stability in aqueous buffer solution. DBCO reagent can be used to label azide modified biomolecules without toxic copper catalyst. Polyethylene glycol can increase the solubility and stability of peptides and proteins, and reduce their immunogenicity. It can also inhibit the nonspecific binding of charged molecules to the modified surface.

相關產品：

DBCO-PEG1K-FITC

DBCO-PEG2K-FITC

DBCO-PEG3.4K-FITC

DBCO-PEG-5K-FITC

DBCO-PEG10K-FITC

DBCO-MPEG1K

DBCO-MPEG2K

DBCO-MPEG3.4K

DBCO-MPEG5K

DBCO-MPEG10K

DBCO-PEG1K-MAL

DBCO-PEG2K-MAL

DBCO-PEG3.4K-MAL

DBCO-PEG5K-MAL

DBCO-PEG10K-MAL

用途:科研

純度:≥95%

保存時間: 1年

產地:西安

供應商：西安齊岳創科生物科技有限公司

注意事項:僅用于科研不用于人體